Taste Masking Agents
Smart Formulations
Turning Bitter Challenges into Pleasant Experiences
COAT ICON ® TM: Our innovative COAT ICON ® TM system offers superior taste masking to enhance the overall medication experience and support patient compliance.
This customized solution is based on a potassium polyacrylate system (Polacrilin Potassium resin), widely used in pharmaceutical formulations. It is particularly effective for masking the bitterness of active pharmaceutical ingredients (APIs) and also serves as a super disintegrant. The mechanism involves forming a complex with the drug, significantly reducing or eliminating unpleasant taste.
| Brand Name | Composition | Usage |
|---|---|---|
|
COAT ICON ® TM |
A mixture of various polymers, such as Polacrilin Potassium, along with other excipients. |
Available in a 1:3 ratio or customized according to the customer’s specific application requirements. |
Versatile Application
From ODTs to Sustained-Release, One Polymer Fits Many Needs
- COAT ICON® TM contains Polacrilin Potassium, a polymer compatible with a wide range of tablet excipients. It can be effectively incorporated into various dosage forms such as orally disintegrating tablets (ODTs), chewable tablets, and sustained-release formulations.
- It is widely used for taste-masking in formulations containing bitter APIs like sildenafil citrate, norfloxacin, clarithromycin, and chloroquine phosphate. The mechanism involves forming a complex with the active drug, thereby significantly reducing or eliminating its unpleasant taste.
- To achieve optimal taste-masking and desired drug release, the drug-to-Polacrilin Potassium ratio must be carefully optimized.
Regulatory Information:
COAT ICON TM is a proprietary blend of Polacrilin Potassium and other pharmaceutical-grade excipients. All components are permitted for use for pharmaceutical applications. However, compliance with regulatory guidelines and safety standards is essential to ensure product efficacy and safety.